Ether NALP3 is similarly needed downstream of a surface MSU-receptor or MSU somehow directly gains access to NALP3 in the cytosol.NIH-PA Author Manuscript NIH-PA Author Manuscript NIH-PA Author ManuscriptAnnu Rev Pathol. Author manuscript; available in PMC 2011 May 13.Rock and KonoPageHost mediators that drive the inflammatory response to dying cellsAfter the initial recognition of a dead cell or
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