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Eliminate the possibility of finding novel inhibitors that indirectly target SecY or SecE. Some currently used antibiotics indirectly target SecY for degradation by stalling protein translation and jamming the SecYEG translocase [97]. Unlike SecY and SecE, there is no eukaryotic homolog of SecA, making it a promising target for inhibitors of Sec export. Inhibitors of in vitro SecA ATPase activity
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