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Tion of HK is triggered by SK, followed by the release of bradykinin.iai.asm.orgInfection and ImmunityAugust 2015 Volume 83 NumberS. pyogenes Streptokinase Triggers Contact ActivationFIG 4 SK induces bradykinin release in plasma. Bradykinin release in dilutedplasma samples was measured after 15 min of incubation with either pSK (100 U) or plasmin (10 g) using an ELISA kit. The bradykinin concentra
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E as a subunit vaccine against HSV-1 infection. DISCUSSION Structural, immunological, and functional studies of the HSV gH-gL complex have been hampered due to the lack of a suitable source of purified protein. Milligram amounts of a truncated mammalian form of HSV-1 gH-gL have now been obtained using a stably transfected L-cell line, HL-7, which secretes gHt and gL as a complex. In agreement with
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On. The clinically evaluable (CE) population comprised c-mITT subjects who met all inclusion/exclusion criteria and had a clinical response of either cure or failure at the test-of-cure (TOC) assessment 8-50 days following the end of therapy (EOT). Subjects with confirmed baseline isolates were included in the microbiologic-modified ITT (m-mITT) and microbiologically evaluable (ME) population, res
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